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Volume 6; 2022

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Research Paper
Design and evaluation of Raman reporters for the Raman-silent region
Konstantinos Plakas, Lauren E. Rosch, Michael D. Clark, Shukree Adbul-Rashed, Travis M. Shaffer, Stefan Harmsen, Sanjiv S. Gambhir, Michael R. Detty
Nanotheranostics 2022; 6: 1-9. doi:10.7150/ntno.58965
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Review
Design and synthesis of gold nanostars-based SERS nanotags for bioimaging applications
Bohdan Andreiuk, Fay Nicolson, Louise M. Clark, Sajanlal R. Panikkanvalappil, Kenry, Mohammad Rashidian, Stefan Harmsen, Moritz F. Kircher
Nanotheranostics 2022; 6: 10-30. doi:10.7150/ntno.61244
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Review
Advances in Surface Enhanced Raman Spectroscopy for in Vivo Imaging in Oncology
Kenry, Fay Nicolson, Louise Clark, Sajanlal R. Panikkanvalappil, Bohdan Andreiuk, Chrysafis Andreou
Nanotheranostics 2022; 6: 31-49. doi:10.7150/ntno.62970
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Review
Review on Optical Imaging Techniques for Multispectral Analysis of Nanomaterials
Haeni Lee, Jaeheung Kim, Hyung-Hoi Kim, Chang-Seok Kim, Jeesu Kim
Nanotheranostics 2022; 6: 50-61. doi:10.7150/ntno.63222
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Research Paper
Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma
Huaijun Wang, Zhongqian Hu, Uday Kumar Sukumar, Rajendran JC Bose, Arsenii Telichko, Jeremy J Dahl, Ramasamy Paulmurugan
Nanotheranostics 2022; 6: 62-78. doi:10.7150/ntno.63320
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Research Paper
Ultrasmall gold nanorod-polydopamine hybrids for enhanced photoacoustic imaging and photothermal therapy in second near-infrared window
Wonjun Yim, Raina M. Borum, Jiajing Zhou, Yash Mantri, Zhuohong Wu, Jingcheng Zhou, Zhicheng Jin, Matthew Creyer, Jesse V. Jokerst
Nanotheranostics 2022; 6: 79-90. doi:10.7150/ntno.63634
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Review
Near-infrared probes for luminescence lifetime imaging
Benhao Li, Jing Lin, Peng Huang, Xiaoyuan Chen
Nanotheranostics 2022; 6: 91-102. doi:10.7150/ntno.63124
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Review
Radiotheranostics - Precision Medicine in Nuclear Medicine and Molecular Imaging
Heying Duan, Andrei Iagaru, Carina Mari Aparici
Nanotheranostics 2022; 6: 103-117. doi:10.7150/ntno.64141
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In Memory
In memory of Michael R. Detty, PhD
David Watson, Stefan Harmsen
Nanotheranostics 2022; 6: 118-120. doi:10.7150/ntno.63716
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In Memory
The brightest stars - a tribute to Moritz Kircher
Chrysafis Andreou
Nanotheranostics 2022; 6: 121-122. doi:10.7150/ntno.63531
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In Memory
A personal tribute to Sanjiv Sam Gambhir MD PHD
Natesh Parashurama
Nanotheranostics 2022; 6: 123-124. doi:10.7150/ntno.67358
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Editorial
Special Issue Dedicated to Dr. Gambhir and Dr. Kircher
Jonathan F Lovell
Nanotheranostics 2022; 6: 125. doi:10.7150/ntno.68107
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Research Paper
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis
Kristen R. Hollinger, Anjali Sharma, Carolyn Tallon, Lyndah Lovell, Ajit G. Thomas, Xiaolei Zhu, Robyn Wiseman, Ying Wu, Siva P. Kambhampati, Kevin Liaw, Rishi Sharma, Camilo Rojas, Rana Rais, Sujatha Kannan, Rangaramanujam M. Kannan, Barbara S. Slusher
Nanotheranostics 2022; 6: 126-142. doi:10.7150/ntno.63158
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Research Paper
Metal-Organic Frameworks for Bioimaging: Strategies and Challenges
Yanfei Liu, Ting Jiang, Zhenbao Liu
Nanotheranostics 2022; 6: 143-160. doi:10.7150/ntno.63458
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Research Paper
Development of CD44E/s dual-targeting DNA aptamer as nanoprobe to deliver treatment in hepatocellular carcinoma
Cario Wing-Sze Lo, Cecilia Ka Wing Chan, Jianqing Yu, Mian He, Chung Hang Jonathan Choi, James Yun Wong Lau, Nathalie Wong
Nanotheranostics 2022; 6: 161-174. doi:10.7150/ntno.62639
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Research Paper
Flavin Adenine Dinucleotide (FAD) Pegylated (PEG)-Complexes: Proof of Concept (PoC) of theranostic tool on a Murine Breast Cancer Model
Celia Arib, Hui Liu, Qiqian Liu, Anne-Marie Cieutat, Didier Paleni, Xiaowu Li, Jolanda Spadavecchia
Nanotheranostics 2022; 6: 175-183. doi:10.7150/ntno.63496
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Review
Biomedical Applications of Lanthanide Nanomaterials, for Imaging, Sensing and Therapy
Qize Zhang, Stephen O'Brien, Jan Grimm
Nanotheranostics 2022; 6: 184-194. doi:10.7150/ntno.65530
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Research Paper
Pharmacokinetic/Pharmacodynamic Determinations of Iron-tannic Molecular Nanoparticles with its Implication in MR Imaging and Enhancement of Liver Clearance
Thipjutha Phatruengdet, Piyachat Khuemjun, Jannarong Intakhad, Saowalak Krunchanuchat, Arpamas Chariyakornkul, Rawiwan Wongpoomchai, Chalermchai Pilapong
Nanotheranostics 2022; 6: 195-204. doi:10.7150/ntno.63310
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Research Paper
Graphene Quantum Dots prepared by Electron Beam Irradiation for Safe Fluorescence Imaging of Tumor
Honghong Cao, Wei Qi, Xudong Gao, Qiang Wu, Longlong Tian, Wangsuo Wu
Nanotheranostics 2022; 6: 205-214. doi:10.7150/ntno.67070
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Research Paper
Lipid nitroalkene nanoparticles for the focal treatment of ischemia reperfusion
Gary Z Yu, Thiruganesh Ramasamy, Marco Fazzari, Xucai Chen, Bruce Freeman, John J Pacella
Nanotheranostics 2022; 6: 215-229. doi:10.7150/ntno.62351
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Research Paper
Mild hyperthermia accelerates doxorubicin clearance from tumour-extravasated temperature-sensitive liposomes
Wafa' T. Al-Jamal, Kostas Kostarelos
Nanotheranostics 2022; 6: 230-242. doi:10.7150/ntno.61280
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Research Paper
Anti-PD-L1 F(ab) Conjugated PEG-PLGA Nanoparticle Enhances Immune Checkpoint Therapy
Christina K. Lee, Danielle F. Atibalentja, Lilian E. Yao, Jangho Park, Sibu Kuruvilla, Dean W. Felsher
Nanotheranostics 2022; 6: 243-255. doi:10.7150/ntno.65544
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Research Paper
Visualizing surface marker expression and intratumoral heterogeneity with SERRS-NPs imaging
Lara K. Rotter, Naxhije Berisha, Hsiao-Ting Hsu, Kathleen H. Burns, Chrysafis Andreou, Moritz F. Kircher
Nanotheranostics 2022; 6: 256-269. doi:10.7150/ntno.67362
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Research Paper
Intracellular vesicle entrapment of nanobubble ultrasound contrast agents targeted to PSMA promotes prolonged enhancement and stability in vivo and in vitro
Reshani H. Perera, Eric Abenojar, Pinunta Nittayacharn, Xinning Wang, Gopal Ramamurthy, Pubudu Peiris, Ilya Bederman, James P. Basilion, Agata A. Exner
Nanotheranostics 2022; 6: 270-285. doi:10.7150/ntno.64735
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Review
Molecular Immune Targeted Imaging of Tumor Microenvironment
Taha Rakhshandehroo, Bryan Ronain Smith, Hannah J. Glockner, Mohammad Rashidian, Neeta Pandit-Taskar
Nanotheranostics 2022; 6: 286-305. doi:10.7150/ntno.66556
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Research Paper
Lanthanide-based β-Tricalcium Phosphate Upconversion Nanoparticles as an Effective Theranostic Nonviral Vectors for Image-Guided Gene Therapy
Flavia Rodrigues Oliveira Silva, Nelson Batista Lima, Maria Helena Bellini, Luiz Felipe Silva Teixeira, Eric Yiwei Du, Niloufar Jamshidi, Justin Gooding, Adam David Martin, Alexander Macmillan, Christopher Peter Marquis, Pall Thordarson
Nanotheranostics 2022; 6: 306-321. doi:10.7150/ntno.68789
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Erratum
Tumor Theranostics of Transition Metal Ions Loaded Polyaminopyrrole Nanoparticles: Erratum
Shuyao Li, Shuwei Liu, Lu Wang, Min Lin, Rui Ge, Xing Li, Xue Zhang, Yi Liu, Lening Zhang, Hongchen Sun, Hao Zhang, Bai Yang
Nanotheranostics 2022; 6: 322-324. doi:10.7150/ntno.67620
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Research Paper
EK-16A liposomes enhance HIV replication in ACH2 or J-Lat 10.6 cell engrafted NSG mice
Panpan Lu, Jinlong Yang, Xinyi Yang, Zhiming Liang, Jing Wang, Yanan Wang, Lin Zhao, Hanyu Pan, Xiaoting Shen, Yuqi Zhu, Jingna Xun, Hongzhou Lu, Huanzhang Zhu
Nanotheranostics 2022; 6: 325-336. doi:10.7150/ntno.69259
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Research Paper
Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue
Priyanka Dey, Alexandra Vaideanu, Sara Mosca, Marzieh Salimi, Benjamin Gardner, Francesca Palombo, Ijeoma Uchegbu, Jeremy Baumberg, Andreas Schatzlein, Pavel Matousek, Nick Stone
Nanotheranostics 2022; 6: 337-349. doi:10.7150/ntno.71510
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Research Paper
A 2D nanotheranostic platform based on graphene oxide and phase-change materials for bimodal CT/MR imaging, NIR-activated drug release, and synergistic thermo-chemotherapy
Mehri Mirrahimi, Zahra Alamzadeh, Jaber Beik, Abolfazl Sarikhani, Mahdie Mousavi, Rasoul Irajirad, Tahereh Khani, Elnaz S. Davani, Ali Farashahi, Tahereh Shakerian Ardakani, Jeff W.M. Bulte, Habib Ghaznavi, Ali Shakeri-Zadeh
Nanotheranostics 2022; 6: 350-364. doi:10.7150/ntno.64790
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Review
Emerging Role of Edible Exosomes-Like Nanoparticles (ELNs) as Hepatoprotective Agents
P. Debishree Subudhi, Chhagan Bihari, Shiv Kumar Sarin, Sukriti Baweja
Nanotheranostics 2022; 6: 365-375. doi:10.7150/ntno.70999
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Research Paper
Ultrasound-triggered oxygen-loaded nanodroplets enhance and monitor cerebral damage from sonodynamic therapy
Harriet Lea-Banks, Sheng-Kai Wu, Hannah Lee, Kullervo Hynynen
Nanotheranostics 2022; 6: 376-387. doi:10.7150/ntno.71946
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Research Paper
Covalent core-radiolabeling of polymeric micelles with 125I/211At for theranostic radiotherapy
Emanuel Sporer, Christian B. M. Poulie, Tom Bäck, Sture Lindegren, Holger Jensen, Paul J. Kempen, Andreas Kjaer, Matthias M. Herth, Andreas I. Jensen
Nanotheranostics 2022; 6: 388-399. doi:10.7150/ntno.71906
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Review
Nanotechnology Advances in the Detection and Treatment of Cancer: An Overview
Sareh Mosleh-Shirazi, Milad Abbasi, Mohammad reza Moaddeli, Ahmad Vaez, Mostafa Shafiee, Seyed Reza Kasaee, Ali Mohammad Amani, Saeid Hatam
Nanotheranostics 2022; 6: 400-423. doi:10.7150/ntno.74613
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Research Paper
Stealth Liposomal Chemotherapeutic Agent for Triple Negative Breast Cancer with Improved Pharmacokinetics
Nagavendra Kommineni, David Paul, Raju Saka, Wahid Khan, Satheeshkumar Nanjappan
Nanotheranostics 2022; 6: 424-435. doi:10.7150/ntno.76370
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Review
Progress on Applying Carbon Dots for Inhibition of RNA Virus Infection
Yaung Kwee, Yiqun Zhou, Mochamad Zakki Fahmi, Madhuri Sharon, Alfinda Novi Kristanti
Nanotheranostics 2022; 6: 436-450. doi:10.7150/ntno.73918
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Research Paper
Comparative effects of free doxorubicin, liposome encapsulated doxorubicin and liposome co-encapsulated alendronate and doxorubicin (PLAD) on the tumor immunologic milieu in a mouse fibrosarcoma model
Md. Rakibul Islam, Jalpa Patel, Patricia Ines Back, Hilary Shmeeda, Konstantin Adamsky, Hui Yang, Carlos Alvarez, Alberto A. Gabizon, Ninh M. La-Beck
Nanotheranostics 2022; 6: 451-464. doi:10.7150/ntno.75045
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