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Volume 5; 2021

Research Paper Cancer-derived EVs show tropism for tissues at early stage of neoplastic transformation Mariangela Garofalo, Alessandro Villa, Electra Brunialti, Daniela Crescenti, Giulia Dell'Omo, Lukasz Kuryk, Andrea Vingiani, Vincenzo Mazzaferro, Paolo Ciana Nanotheranostics 2021; 5: 1-7. doi:10.7150/ntno.47226 Full text PDF PubMed PMC

Research Paper Neural precursors cells expanded in a 3D micro-engineered niche present enhanced therapeutic efficacy in vivo Stephana Carelli, Toniella Giallongo, Federica Rey, Bianca Barzaghini, Tommaso Zandrini, Andrea Pulcinelli, Riccardo Nardomarino, Giulio Cerullo, Roberto Osellame, Cristina Cereda, Gian Vincenzo Zuccotti, Manuela Teresa Raimondi Nanotheranostics 2021; 5: 8-26. doi:10.7150/ntno.50633 Full text PDF PubMed PMC

Review Imaging of cell-based therapy using ⁸⁹Zr-oxine ex vivo cell labeling for positron emission tomography Yutaka Kurebayashi, Peter L. Choyke, Noriko Sato Nanotheranostics 2021; 5: 27-35. doi:10.7150/ntno.51391 Full text PDF PubMed PMC

Research Paper Macrophage imaging and subset analysis using single-cell RNA sequencing Sean Arlauckas, Nuri Oh, Ran Li, Ralph Weissleder, Miles A. Miller Nanotheranostics 2021; 5: 36-56. doi:10.7150/ntno.50185 Full text PDF PubMed PMC

Research Paper Intraoperative assessment and postsurgical treatment of prostate cancer tumors using tumor-targeted nanoprobes James Teh, Manisha Tripathi, Derek Reichel, Bien Sagong, Ricardo Montoya, Yi Zhang, Shawn Wagner, Rola Saouaf, Leland W. K. Chung, J. Manuel Perez Nanotheranostics 2021; 5: 57-72. doi:10.7150/ntno.50095 Full text PDF PubMed PMC

Review Multifunctional microfluidic chip for cancer diagnosis and treatment Qiao-ru Guo, Ling-ling Zhang, Ji-fang Liu, Zhen Li, Jia-jun Li, Wen-min Zhou, Hui Wang, Jing-quan Li, Da-yu Liu, Xi-yong Yu, Jian-ye Zhang Nanotheranostics 2021; 5: 73-89. doi:10.7150/ntno.49614 Full text PDF PubMed PMC

Review Noninvasive Imaging of Cancer Immunotherapy Omar Abousaway, Taha Rakhshandehroo, Annick D. Van den Abbeele, Moritz F. Kircher, Mohammad Rashidian Nanotheranostics 2021; 5: 90-112. doi:10.7150/ntno.50860 Full text PDF PubMed PMC

Research Paper Resveratrol loaded polymeric micelles for theranostic targeting of breast cancer cells Yiota Gregoriou, Gregoria Gregoriou, Vural Yilmaz, Konstantinos Kapnisis, Marianna Prokopi, Andreas Anayiotos, Katerina Strati, Nikolas Dietis, Andreas I. Constantinou, Chrysafis Andreou Nanotheranostics 2021; 5: 113-124. doi:10.7150/ntno.51955 Full text PDF PubMed PMC

Research Paper MR-labelled liposomes and focused ultrasound for spatiotemporally controlled drug release in triple negative breast cancers in mice Maral Amrahli, Miguel Centelles, Paul Cressey, Martynas Prusevicius, Wladyslaw Gedroyc, Xiao Yun Xu, Po-Wah So, Michael Wright, Maya Thanou Nanotheranostics 2021; 5: 125-142. doi:10.7150/ntno.52168 Full text PDF PubMed PMC

Research Paper Resveratrol and its Nanoparticle suppress Doxorubicin/Docetaxel-resistant anaplastic Thyroid Cancer Cells in vitro and in vivo Le Xiong, Xiao-Min Lin, Jun-Hua Nie, Hai-Shan Ye, Jia Liu Nanotheranostics 2021; 5: 143-154. doi:10.7150/ntno.53844 Full text PDF PubMed PMC

Review Strategies for the functionalisation of gold nanorods to reduce toxicity and aid clinical translation Xin Shi, Hannah L. Perry, James D. E. T. Wilton-Ely Nanotheranostics 2021; 5: 155-165. doi:10.7150/ntno.56432 Full text PDF PubMed PMC

Research Paper Non-invasive multimodal imaging of Diabetic Retinopathy: A survey on treatment methods and Nanotheranostics Rajkumar Sadasivam, Gopinath Packirisamy, Snehlata Shakya, Mayank Goswami Nanotheranostics 2021; 5: 166-181. doi:10.7150/ntno.56015 Full text PDF PubMed PMC

Research Paper Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors Ethel J. Ngen, Ying Chen, Babak Behnam Azad, Srikanth Boinapally, Desmond Jacob, Ala Lisok, Chentian Shen, Mir S. Hossain, Jiefu Jin, Zaver M. Bhujwalla, Martin G. Pomper, Sangeeta R. Banerjee Nanotheranostics 2021; 5: 182-196. doi:10.7150/ntno.52361 Full text PDF PubMed PMC

Research Paper Cyclodextrin nanosponge for the GSH-mediated delivery of Resveratrol in human cancer cells Marco Palminteri, Nilesh Kumar Dhakar, Alessandra Ferraresi, Fabrizio Caldera, Chiara Vidoni, Francesco Trotta, Ciro Isidoro Nanotheranostics 2021; 5: 197-212. doi:10.7150/ntno.53888 Full text PDF PubMed PMC

Research Paper Nanotheranostics through Mitochondria-targeted Delivery with Fluorescent Peptidomimetic Nanohybrids for Apoptosis Induction of Brain Cancer Cells Isadora C. Carvalho, Alexandra A. P. Mansur, Sandhra M. Carvalho, Herman S. Mansur Nanotheranostics 2021; 5: 213-239. doi:10.7150/ntno.54491 Full text PDF PubMed PMC

Research Paper Non-radioactive and sensitive tracking of neutrophils towards inflammation using antibody functionalized magnetic particle imaging tracers Prashant Chandrasekharan, K.L. Barry Fung, Xinyi Y. Zhou, Weiwen Cui, Caylin Colson, David Mai, Kenneth Jeffris, Quincy Huynh, Chinmoy Saayujya, Leyla Kabuli, Benjamin Fellows, Yao Lu, Elaine Yu, Zhi Wei Tay, Bo Zheng, Lawrence Fong, Steven M. Conolly Nanotheranostics 2021; 5: 240-255. doi:10.7150/ntno.50721 Full text PDF PubMed PMC

Review Radiolabelling of Extracellular Vesicles for PET and SPECT imaging Azalea A. Khan, Rafael T. M. de Rosales Nanotheranostics 2021; 5: 256-274. doi:10.7150/ntno.51676 Full text PDF PubMed PMC

Research Paper Cell membrane coated smart two-dimensional supraparticle for in vivo homotypic cancer targeting and enhanced combinational theranostics Di Zhang, Zhongju Ye, Hua Liu, Xin Wang, Jianhao Hua, Yunyun Ling, Lin Wei, Yunsheng Xia, Shaokai Sun, Lehui Xiao Nanotheranostics 2021; 5: 275-287. doi:10.7150/ntno.57657 Full text PDF PubMed PMC

Review Review of nanotheranostics for molecular mechanisms underlying psychiatric disorders and commensurate nanotherapeutics for neuropsychiatry: The mind knockout Rajiv Kumar, Bhupender S Chhikara, Kiran Gulia, Mitrabasu Chhillar Nanotheranostics 2021; 5: 288-308. doi:10.7150/ntno.49619 Full text PDF PubMed PMC

Research Paper Pulmonary fate and consequences of transferrin-functionalized gold nanoparticles Nagarjun Venkata Konduru, Karen Velasco-Alzate, Sitaramaraju Adduri, Kyryl Zagorovsky, Daysi Diaz-Diestra, Faisalina Fisol, Marcelo Sanches, Harrison Ndetan, Joseph David Brain, Ramon Morales Molina Nanotheranostics 2021; 5: 309-320. doi:10.7150/ntno.47734 Full text PDF PubMed PMC

Review The unfavorable role of titanium particles released from dental implants Zilan Zhou, Quan Shi, Jie Wang, Xiaohang Chen, Yujia Hao, Yuan Zhang, Xing Wang Nanotheranostics 2021; 5: 321-332. doi:10.7150/ntno.56401 Full text PDF PubMed PMC

Research Paper Nanoparticles exhibiting self-regulating temperature as innovative agents for Magnetic Fluid Hyperthermia Marco Gerosa, Marco Dal Grande, Alice Busato, Federica Vurro, Barbara Cisterna, Enrico Forlin, Filippo Gherlinzoni, Giovanni Morana, Michele Gottardi, Paolo Matteazzi, Adolfo Speghini, Pasquina Marzola Nanotheranostics 2021; 5: 333-347. doi:10.7150/ntno.55695 Full text PDF PubMed PMC

Research Paper Long circulating tracer tailored for magnetic particle imaging Sitong Liu, Andreina Chiu-Lam, Angelie Rivera-Rodriguez, Ryan DeGroff, Shehaab Savliwala, Nicole Sarna, Carlos M. Rinaldi-Ramos Nanotheranostics 2021; 5: 348-361. doi:10.7150/ntno.58548 Full text PDF PubMed PMC

Research Paper Biodegradable polyelectrolyte/magnetite capsules for MR imaging and magnetic targeting of tumors Yulia Svenskaya, Francesca Garello, Ekaterina Lengert, Anastasiia Kozlova, Roman Verkhovskii, Valeria Bitonto, Maria Rosaria Ruggiero, Sergey German, Dmitry Gorin, Enzo Terreno Nanotheranostics 2021; 5: 362-377. doi:10.7150/ntno.59458 Full text PDF PubMed PMC

Research Paper Engineering Extracellular Vesicles to Target Pancreatic Tissue In Vivo Hiroaki Komuro, Yuki Kawai-Harada, Shakhlo Aminova, Nathaniel Pascual, Anshu Malik, Christopher H. Contag, Masako Harada Nanotheranostics 2021; 5: 378-390. doi:10.7150/ntno.54879 Full text PDF PubMed PMC

Research Paper Therapeutic Efficacy of Lactonic Sophorolipids: Nanoceria-Assisted Combination Therapy of NSCLC using HDAC and Hsp90 Inhibitors Shuguftha Naz, Tuhina Banerjee, Filbert Totsingan, Kalee Woody, Richard A. Gross, Santimukul Santra Nanotheranostics 2021; 5: 391-404. doi:10.7150/ntno.57675 Full text PDF PubMed PMC

Research Paper A Pegylated Flavin Adenine Dinucleotide PEG Complex to Boost Immunogenic and Therapeutic Effects in a Liver Cancer Model Celia Arib, Hui Liu, Qiqian Liu, Anne-Marie Cieutat, Didier Paleni, Xiaowu Li, Jolanda Spadavecchia Nanotheranostics 2021; 5: 405-416. doi:10.7150/ntno.59290 Full text PDF PubMed PMC

Research Paper Europium sulfide nanoprobes predict antiretroviral drug delivery into HIV-1 cell and tissue reservoirs Jonathan Herskovitz, Mahmudul Hasan, Jatin Machhi, Insiya Mukadam, Brendan M. Ottemann, James R. Hilaire, Christopher Woldstad, JoEllyn McMillan, Yutong Liu, Javier Seravalli, Anandakumar Sarella, Howard E. Gendelman, Bhavesh D. Kevadiya Nanotheranostics 2021; 5: 417-430. doi:10.7150/ntno.59568 Full text PDF PubMed PMC

Research Paper Tracking adoptive T cell immunotherapy using magnetic particle imaging Angelie Rivera-Rodriguez, Lan B. Hoang-Minh, Andreina Chiu-Lam, Nicole Sarna, Leyda Marrero-Morales, Duane A. Mitchell, Carlos M. Rinaldi-Ramos Nanotheranostics 2021; 5: 431-444. doi:10.7150/ntno.55165 Full text PDF PubMed PMC

Letter Pentraxin 3: a powerful orchestrator in urinary tract infection Cheng Qiu, Tianyi Liu, Dan Luo, Zhaoxiang Xie Nanotheranostics 2021; 5: 445-447. doi:10.7150/ntno.60901 Full text PDF PubMed PMC

Research Paper Carbohydrate based biomarkers enable hybrid near infrared fluorescence and ⁶⁴Cu based radio-guidance for improved surgical precision Wenbo Wang, Anders E. Hansen, Hongmei Sun, Frederikke P. Fliedner, Andreas Kjaer, Andreas I. Jensen, Thomas L. Andresen, Jonas R. Henriksen Nanotheranostics 2021; 5: 448-460. doi:10.7150/ntno.60295 Full text PDF PubMed PMC

Review Nanotheranostic Application of Fluorescent Protein-Gold Nanocluster Hybrid Materials: A Mini-review Han Ding, Zhijun Chen Nanotheranostics 2021; 5: 461-471. doi:10.7150/ntno.58060 Full text PDF PubMed PMC

Research Paper Photoactive Silver Nanoagents for Backgroundless Monitoring and Precision Killing of Multidrug-Resistant Bacteria Zhiwen Xu, Cai Zhang, Yunjian Yu, Wenshuai Li, Zhuang Ma, Jingjing Wang, Xinge Zhang, Hongmei Gao, Dingbin Liu Nanotheranostics 2021; 5: 472-487. doi:10.7150/ntno.62364 Full text PDF PubMed PMC

Research Paper Novel Protocols for Scalable Production of High Quality Purified Small Extracellular Vesicles from Bovine Milk Spencer R. Marsh, Kevin J. Pridham, Jane Jourdan, Robert G. Gourdie Nanotheranostics 2021; 5: 488-498. doi:10.7150/ntno.62213 Full text PDF PubMed PMC

Research Paper Recent Advances in the Development of Theranostic Nanoparticles for Cardiovascular Diseases Yuao Wu, Karla X. Vazquez-Prada, Yajun Liu, Andrew K. Whittaker, Run Zhang, Hang T. Ta Nanotheranostics 2021; 5: 499-514. doi:10.7150/ntno.62730 Full text PDF PubMed PMC