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Nanotheranostics, the sister journal of Theranostics, is a multidisciplinary and fully open access journal. Currently, the journal does not charge any publication or submission fees (Platinum open access). Nanotheranostics publishes innovative and original basic, translational and clinical research reflecting the fields of nanomedicine, nanoimaging, drug and gene delivery, nanoelectronic biosensors, and other areas. 

Regular features include high quality research articles, reviews or mini-reviews, rapid communication of preliminary data on innovative research, editorials, and letters to the editor. Educational articles on basic sciences, fundamental aspects and controversy related to pre-clinical and clinical studies or ethical issues of nanomedicine are also welcome. Timely reviews that provide updates on current applications and issues in nanomedicine and translational aspects of nanotheranostics and other topics are particularly welcome and will be given high priority.

Nanotheranostics employs a rigorous peer-review system, but also strives for rapid review turnaround times and is based on the same streamlined submission platform as Theranostics.

Recent Papers:


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Research Paper
Biodistribution and acute toxicity of cadmium-free quantum dots with different surface functional groups in mice following intratracheal inhalation
Guimiao Lin, Ting Chen, Yongning Pan, Zhiwen Yang, Li Li, Ken-tye Yong, Xiaomei Wang, Jie Wang, Yajing Chen, Wenxiao Jiang, Shuting Weng, Xiaorui Huang, Jiajie Kuang, Gaixia Xu
Nanotheranostics 2020; 4(3): 173-183. doi:10.7150/ntno.42786
[Abstract] [Full text] [PDF]


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Research Paper
Supramolecular Polysaccharide Nanotheranostics that Inhibit Cancer Cells Growth and Monitor Targeted Therapy Response
Nilesh Deshpande, Anujan Ramesh, Dipika Nandi, Anh Nguyen, Anthony Brouillard, Ashish Kulkarni
Nanotheranostics 2020; 4(3): 156-172. doi:10.7150/ntno.44703
[Abstract] [Full text] [PDF]


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Research Paper
Preclinical evaluation of cationic DOTA-triarginine-lipid conjugates for theranostic liquid brachytherapy
Wenbo Wang, Frederikke P. Fliedner, Anders E. Hansen, Rasmus Eliasen, Fredrik Melander, Andreas Kjaer, Thomas L. Andresen, Andreas I. Jensen, Jonas R. Henriksen
Nanotheranostics 2020; 4(3): 142-155. doi:10.7150/ntno.44562
[Abstract] [Full text] [PDF]


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Research Paper
Multicolor spectral photon counting CT monitors and quantifies therapeutic cells and their encapsulating scaffold in a model of brain damage
Elisa Cuccione, Peter Chhour, Salim Si-Mohamed, Chloé Dumot, Johoon Kim, Violaine Hubert, Claire Crola Da Silva, Marc Vandamme, Emmanuel Chereul, Joëlle Balegamire, Yves Chevalier, Yves Berthezène, Loïc Boussel, Philippe Douek, David P. Cormode, Marlène Wiart
Nanotheranostics 2020; 4(3): 129-141. doi:10.7150/ntno.45354
[Abstract] [Full text] [PDF]


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Research Paper
Establishment of a hTfR mAb-functionalized HPPS theranostic nanoplatform
Qi He, Zilong Guo, Mingpeng Fu, Hongling Tang, Huifen Zhu, Guanxin Shen, Yong He, Ping Lei
Nanotheranostics 2020; 4(3): 119-128. doi:10.7150/ntno.41741
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Binding of Targeted Semiconducting Photothermal Polymer Nanoparticles for Intraperitoneal Detection and Treatment of Colorectal Cancer
Eleanor McCabe-Lankford, Bryce McCarthy, Margarita Arakelyan- Peters Berwick, Kiarash Salafian, Laura Galarza-Paez, Santu Sarkar, John Sloop, George Donati, April J. Brown, Nicole Levi-Polyachenko
Nanotheranostics 2020; 4(3): 107-118. doi:10.7150/ntno.29522
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Liposome-Templated Indocyanine Green J- Aggregates for In Vivo Near Infrared Imaging and Stable Photothermal Heating
Calvin C. L. Cheung, Guanglong Ma, Kostas Karatasos, Jani Seitsonen, Janne Ruokolainen, Cédrik-Roland Koffi, Hatem A.F.M Hassan, Wafa' T. Al-Jamal
Nanotheranostics 2020; 4(2): 91-106. doi:10.7150/ntno.41737
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Phospholipid Oxygen Microbubbles for Image-Guided Therapy
Traci D. Reusser, Kang-Ho Song, David Ramirez, Richard KP Benninger, Virginie Papadopoulou, Mark A. Borden
Nanotheranostics 2020; 4(2): 83-90. doi:10.7150/ntno.43808
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Organ Biodistribution of Radiolabelled γδ T Cells Following Liposomal Alendronate Administration in Different Mouse Tumour Models
Julie T-W. Wang, Naomi O. Hodgins, Wafa' T. Al-Jamal, John Maher, Jane K. Sosabowski, Khuloud T. Al-Jamal
Nanotheranostics 2020; 4(2): 71-82. doi:10.7150/ntno.32876
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Effects of molecular weight and structural conformation of multivalent-based elastin-like polypeptides on tumor accumulation and tissue biodistribution
Vijaya Sarangthem, Bo-Yeon Seo, Aena Yi, Young-Jin Lee, Sun-Ha Cheon, Sang Kyoon Kim, Thoudam Debraj Singh, Byung-Heon Lee, Rang-Woon Park
Nanotheranostics 2020; 4(2): 57-70. doi:10.7150/ntno.39804
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Phospholipid prodrug conjugates of insoluble chemotherapeutic agents for ultrasound targeted drug delivery
Mendi G. Márquez, Rachel Dotson, Sally Pias, Liliya V. Frolova, Michaelann S. Tartis
Nanotheranostics 2020; 4(1): 40-56. doi:10.7150/ntno.37738
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
FGF2 engineered SPIONs attenuate tumor stroma and potentiate the effect of chemotherapy in 3D heterospheroidal model of pancreatic tumor
Deby Fajar Mardhian, Aggelos Vrynas, Gert Storm, Ruchi Bansal, Jai Prakash
Nanotheranostics 2020; 4(1): 26-39. doi:10.7150/ntno.38092
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Uptake and subcellular distribution of radiolabeled polymersomes for radiotherapy
Stefan J. Roobol, Thomas A. Hartjes, Johan A. Slotman, Robin M. de Kruijff, Guzman Torrelo, T.E. Abraham, Frank Bruchertseifer, Alfred Morgenstern, Roland Kanaar, Dik C. van Gent, Adriaan B. Houtsmuller, Antonia G. Denkova, Martin E. van Royen, Jeroen Essers
Nanotheranostics 2020; 4(1): 14-25. doi:10.7150/ntno.37080
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Thermo-responsive Fluorescent Nanoparticles for Multimodal Imaging and Treatment of Cancers
Nikhil Pandey, Jyothi U. Menon, Masaya Takahashi, Jer-Tsong Hsieh, Jian Yang, Kytai T. Nguyen, Aniket S. Wadajkar
Nanotheranostics 2020; 4(1): 1-13. doi:10.7150/ntno.39810
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Nano-Antagonist Alleviates Inflammation and Allows for MRI of Atherosclerosis
Brian Mog, Courteney Asase, Alice Chaplin, Huiyun Gao, Sanjay Rajagopalan, Andrei Maiseyeu
Nanotheranostics 2019; 3(4): 342-355. doi:10.7150/ntno.37391
[Abstract] [Full text] [PDF] [PubMed] [PMC]


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Research Paper
Microbubble enhanced ultrasound for the antivascular treatment and monitoring of hepatocellular carcinoma
Julia C. D'Souza, Laith R. Sultan, Stephen J. Hunt, Terence P. Gade, Mrigendra B. Karmacharya, Susan M. Schultz, Angela K. Brice, Andrew K. W. Wood, Chandra M. Sehgal
Nanotheranostics 2019; 3(4): 331-341. doi:10.7150/ntno.39514
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Editor-in-Chief:
Moritz F. Kircher, MD, PhD
Chair, Department of Imaging and Radiology
Dana-Farber Cancer Institute &
Harvard Medical School
Editor-in-chief profile
new Nanotheranostics is now indexed in the Web of Science, Biological Abstracts and BIOSIS Previews.

Nanotheranostics has been selected by The Literature Selection Technical Review Committee (LSTRC) for inclusion in MEDLINE, the prestigious index of U.S. National Library of Medicine.

Stem cell transplants are an effective approach to repair large bone defects. However, comprehensive techniques to monitor the fate of transplanted stem cells in vivo are lacking. Such strategies would enable corrective interventions at an early stage and greatly benefit the development of more successful tissue regeneration approaches. In this study, we designed and synthesized a dual-modality imaging probe (Feru-AFC) that can simultaneously localize transplanted stem cells and diagnose immune rejection-induced apoptosis at an early stage in vivo. ...
Endoscopy is the gold standard investigation in the diagnosis of gastrointestinal cancers and the management of early and pre-malignant lesions either by resection or ablation. Recently gold nanoparticles have shown promise in cancer diagnosis and therapeutics (theranostics). The combination of multifunctional gold nanoparticles with near infrared fluorescence endoscopy for accurate mapping of early or pre-malignant lesions can potentially enhance diagnostic efficiency while precisely directing endoscopic near infrared photothermal therapy for established cancers. ...
Squalenoylation of gemcitabine, a front-line therapy for pancreatic cancer, allows for improved cellular-level and system-wide drug delivery. The established methods to conjugate squalene to gemcitabine and to form nanoparticles (NPs) with the squalenoylated gemcitabine (SqGem) conjugate are cumbersome, time-consuming and can be difficult to reliably replicate. Further, the creation of multi-functional SqGem-based NP theranostics would facilitate characterization of in vivo pharmacokinetics and efficacy. More ...
Anticancer nanotherapeutics have shown mixed results in clinical trials, raising the questions of whether imaging should be used to i) identify patients with a higher likelihood of nanoparticle accumulation, ii) assess nanotherapeutic efficacy before traditional measures show response, and iii) guide adjuvant treatments to enhance therapeutic nanoparticle (TNP) delivery. Here we review the use of a clinically approved MRI nanoparticle (ferumoxytol, FMX) to predict TNP delivery and efficacy. It is becoming increasingly apparent that nanoparticles used for imaging, despite clearly distinct physicochemical properties, often co-localize with TNP in tumors. This evidence offers the possibility of using FMX as a generic “companion diagnostic” nanoparticle for multiple TNP formulations, thus potentially allowing many of the complex regulatory and cost challenges of other approaches to be avoided. More ...
Congratulations to Dr. Chen for being elected as AIMBE fellow: http://aimbe.org/college-of-fellows/cof-2103/
Congratulations to Dr. Chen for being recognized as Selected Highly Prolific Authors  (most published articles in the past 5 years) for 3 ACS journals (ACS Nano, Bioconjugate Chemistry, and Molecular Pharmaceutics). More details: http://journalstars.acs.org/