Nanotheranostics 2017; 1(3):272-295. doi:10.7150/ntno.20301 This issue


Recent Advances in Biosensor Development for Foodborne Virus Detection

Suresh Neethirajan1✉, Syed Rahin Ahmed1, Rohit Chand1, John Buozis1, Éva Nagy2

1. BioNano Laboratory, School of Engineering, University of Guelph, Guelph, ON N1G 2W1, Canada;
2. Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada.

This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license ( See for full terms and conditions.
Neethirajan S, Ahmed SR, Chand R, Buozis J, Nagy É. Recent Advances in Biosensor Development for Foodborne Virus Detection. Nanotheranostics 2017; 1(3):272-295. doi:10.7150/ntno.20301. Available from

File import instruction


Graphic abstract

Outbreaks of foodborne diseases related to fresh produce have been increasing in North America and Europe. Viral foodborne pathogens are poorly understood, suffering from insufficient awareness and surveillance due to the limits on knowledge, availability, and costs of related technologies and devices. Current foodborne viruses are emphasized and newly emerging foodborne viruses are beginning to attract interest. To face current challenges regarding foodborne pathogens, a point-of-care (POC) concept has been introduced to food testing technology and device. POC device development involves technologies such as microfluidics, nanomaterials, biosensors and other advanced techniques. These advanced technologies, together with the challenges in developing foodborne virus detection assays and devices, are described and analysed in this critical review. Advanced technologies provide a path forward for foodborne virus detection, but more research and development will be needed to provide the level of manufacturing capacity required.

Keywords: Foodborne virus, microfluidics, nanomaterials, biosensor, point-of-care.